Title: Amenable L2-signatures and cobordism of knots and 3-manifolds Abstract: Recently, new amenable Cheeger-Gromov rho-invariants have been introduced to study homology cobordism of 3-manifolds and concordance of knots and links. This reveals new structures beyond those visible via Cochran-Orr-Teichner type signatures. We introduce the key ideas of amenable L2 methods and some applications. Also, if time permits, we discuss the notion of symmetric Whitney tower cobordism which provides a generalized framework for bordered 3-manifolds and link concordance. Parts of the results in this talk are joint with Kent Orr.